What Are the Challenges in Using Antiepileptic Drugs in Neonates?
One of the primary challenges in using AEDs in neonates is the lack of extensive clinical trials and evidence-based guidelines specifically tailored to this population. Additionally, the pharmacokinetics of drugs in neonates can be unpredictable due to their developing organ systems. Monitoring levels and adjusting doses can be complex but are necessary to minimize side effects and ensure efficacy.