How Are Antiepileptic Drugs Administered to Neonates?
AEDs are typically administered intravenously in the acute setting. Phenobarbital is often given as a loading dose followed by maintenance doses. Phenytoin is also administered intravenously but requires careful monitoring of cardiac function. Levetiracetam can be given intravenously or orally, depending on the clinical situation. Precise dosing and administration are critical, given the unique pharmacokinetics in neonates.
