Early detection of neonatal disorders through the heel prick test can significantly improve the prognosis and quality of life for affected infants. Conditions such as [Phenylketonuria](href), [Congenital Hypothyroidism](href), [Cystic Fibrosis](href), and [Sickle Cell Disease](href) can lead to severe developmental issues, intellectual disabilities, or even death if not treated promptly. Early intervention can mitigate these risks and allow for more effective management of the disorders.