Why are Histone Demethylase Inhibitors Relevant in Pediatrics?
Pediatric patients often deal with unique diseases and conditions that may not be prevalent or as severe in adults. For instance, certain types of pediatric cancers, such as neuroblastoma and medulloblastoma, involve aberrant histone modifications. Histone demethylase inhibitors offer a promising therapeutic avenue for these conditions by potentially reversing the abnormal gene expression patterns that contribute to tumor growth and progression.
