What Role Do Molecular Mechanisms Play in Developmental Disorders?
Developmental disorders often stem from disruptions in molecular signaling pathways during critical periods of growth. For example, mutations in the SHANK3 gene are associated with Phelan-McDermid syndrome, a neurodevelopmental disorder. This gene is crucial for normal synaptic function, and its disruption can lead to intellectual disability and autism spectrum disorders. Understanding these molecular underpinnings can inform early diagnosis and intervention strategies.
