How Are Molecular Mechanisms Studied in Pediatric Research?
Various techniques are employed to study molecular mechanisms, including:
- Genomics: Sequencing technologies, such as whole-exome sequencing, can identify mutations associated with pediatric diseases. - Proteomics: Mass spectrometry helps in studying protein expression and modifications. - Transcriptomics: RNA sequencing provides insights into gene expression profiles. - Functional assays: Techniques like CRISPR-Cas9 allow researchers to manipulate genes and observe resulting phenotypes.
These methods collectively enable a comprehensive understanding of the molecular basis of pediatric conditions.