What Role Do Excipients Play in Pediatric Formulations?
Excipients are inactive substances used as carriers for the active ingredients of a medication. However, some excipients that are safe for adults can be toxic to children. For instance, benzyl alcohol has been associated with "gasping syndrome" in neonates, and propylene glycol can cause hyperosmolarity. Therefore, excipients must be carefully selected and evaluated for safety in pediatric populations.