What is Fluorescence In Situ Hybridization (FISH)?
Fluorescence In Situ Hybridization (FISH) is a powerful molecular cytogenetic technique that allows for the detection and localization of specific DNA sequences on chromosomes. This method uses fluorescently labeled DNA probes to bind to their complementary sequences within a cell. When viewed under a fluorescence microscope, these probes emit light, making the specific regions of the chromosomes visible.