Which Neonatal Disorders can be Diagnosed Using FISH?
FISH is used to diagnose a variety of neonatal disorders with genetic origins, such as:
Down Syndrome: Caused by an extra copy of chromosome 21, FISH can quickly confirm the presence of trisomy 21. DiGeorge Syndrome: Associated with deletions on chromosome 22q11.2, FISH can identify these microdeletions. Prader-Willi and Angelman Syndromes: Both conditions involve abnormalities in chromosome 15, which FISH can detect. Cri-du-chat Syndrome: Caused by a deletion on the short arm of chromosome 5, easily detectable by FISH.
