Bicarbonate therapy is typically administered intravenously in a clinical setting. The dosage and rate of administration depend on the severity of acidosis and the neonate's overall condition. The following steps are generally followed:
1. Assessment: Blood gas analysis is performed to determine pH, bicarbonate levels, and the presence of metabolic acidosis. 2. Calculation: The required dose of bicarbonate is calculated based on the infantâs weight and the base deficit. 3. Administration: Sodium bicarbonate is administered slowly via an intravenous line to prevent rapid shifts in pH, which can be harmful.