The transfer of DMARDs into breast milk and their potential effects on the neonate are important considerations. For instance:
- Hydroxychloroquine and Sulfasalazine are usually considered safe for breastfeeding. - Methotrexate is contraindicated due to its potential toxicity. - Biologic DMARDs generally have large molecular structures, which makes it less likely for them to transfer into breast milk in significant amounts. However, each biologic should be evaluated on a case-by-case basis.