Are There Any Challenges in Targeting RISC in Pediatrics?
While the therapeutic potential of targeting RISC is significant, there are several challenges to overcome. One of the primary challenges is the efficient delivery of siRNA or miRNA molecules to the target cells without causing off-target effects or immune responses. Additionally, the safety and long-term effects of manipulating the RISC pathway in growing children need to be thoroughly evaluated. Ongoing research is focused on developing safer and more effective delivery systems and understanding the broader implications of RISC modulation.