What Pediatric Conditions Are Associated with miR-34a?
Research has identified several pediatric conditions where miR-34a plays a significant role:
Neuroblastoma: miR-34a has been shown to function as a tumor suppressor. Altered levels of miR-34a can affect tumor growth and response to treatment. Medulloblastoma: Similar to neuroblastoma, miR-34a may influence tumor behavior and could serve as a potential biomarker for diagnosis and prognosis. Congenital Heart Disease: Aberrations in miR-34a expression have been linked to improper heart development. Developmental Disorders: Dysregulated miR-34a expression can affect neural development, potentially leading to conditions like autism or intellectual disabilities.
