The mainstay of treatment for syphilis in children is antibiotic therapy, specifically penicillin. The regimen depends on the age of the child and the stage of the disease:
Infants: Newborns with congenital syphilis are treated with intravenous or intramuscular penicillin for 10-14 days. Older Children: The treatment involves a single intramuscular injection of benzathine penicillin G. However, if the infection is late latent or of unknown duration, a prolonged course may be needed.
