pharmacodynamics

Why is Pharmacodynamics Different in Neonates?

Neonates exhibit different drug responses compared to older children and adults due to several factors:
Body Composition: Neonates have a higher water content and lower fat percentage, which affects drug distribution.
Organ Maturity: Immature liver and kidney functions can impact drug metabolism and excretion.
Enzyme Activity: Reduced activity of metabolic enzymes can prolong the effects of certain drugs.

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