In the field of Pediatrics, IGF2 is significant because it is heavily involved in regulating fetal and early childhood development. Abnormalities in IGF2 expression can lead to various developmental disorders. For example, overexpression or mutations in the IGF2 gene can contribute to conditions like Beckwith-Wiedemann Syndrome (BWS), which is characterized by overgrowth and an increased risk of developing certain cancers.
