In neonates, certain genetic and congenital disorders can severely affect the bone marrow's ability to produce healthy blood cells. Conditions like Severe Combined Immunodeficiency (SCID), congenital leukemias, and metabolic disorders like Hurler Syndrome may necessitate the use of HSCT. The transplant aims to provide the infant with a new, functional bone marrow that can produce healthy blood cells and improve or cure the underlying disease.
