What Pediatric Conditions can Benefit from HDAC Inhibitors?
- Cancer: HDAC inhibitors have been studied in pediatric oncology for their ability to induce cancer cell death and enhance the efficacy of existing chemotherapy agents. - Neurodevelopmental Disorders: Conditions such as Rett syndrome, a severe neurodevelopmental disorder, have shown potential responsiveness to HDAC inhibitors in preclinical studies. - Genetic Syndromes: Certain genetic disorders that involve dysregulated gene expression may benefit from HDAC inhibitor therapy. - Inflammatory Conditions: Emerging research suggests that HDAC inhibitors might play a role in managing inflammatory diseases in children by modulating immune responses.
