Histone deacetylase inhibitors (HDAC inhibitors) are a class of compounds that interfere with the function of histone deacetylase enzymes. These enzymes play a crucial role in the regulation of gene expression by removing acetyl groups from histone proteins, leading to a condensed and transcriptionally silent chromatin. By inhibiting HDAC, these drugs can induce a more relaxed chromatin state, promoting the expression of specific genes that can lead to various therapeutic effects.
