What is the Role of TNF Alpha in Necrotizing Enterocolitis?
Necrotizing enterocolitis (NEC) is a gastrointestinal emergency in neonates, primarily affecting premature infants. The pathogenesis of NEC involves an exaggerated inflammatory response, in which TNF Alpha plays a pivotal role. Elevated levels of TNF Alpha contribute to intestinal inflammation, leading to bowel necrosis. Strategies to modulate TNF Alpha levels are being researched as potential therapies to mitigate the severity of NEC.
