The prognosis for neonates with GSD varies widely depending on the type and severity of the disease: - GSD Type I: With appropriate management, many individuals can lead relatively normal lives, though they may have ongoing challenges. - Pompe Disease: Early initiation of enzyme replacement therapy can significantly improve outcomes, particularly in the infantile-onset form. - GSD Type III and IV: These types may have a more variable prognosis, with some patients experiencing progressive liver or muscle disease.