Immature kidney function in neonates and infants refers to the underdeveloped ability of the kidneys to filter blood, regulate electrolytes, and maintain fluid balance. The glomerular filtration rate (GFR) in neonates is significantly lower than in adults, which means that their kidneys are less efficient at excreting waste products and drugs. This immaturity can affect fluid and electrolyte management, acid-base balance, and drug clearance.
