What Challenges Exist in Applying CONSORT Guidelines to Pediatric Studies?
Applying CONSORT guidelines to pediatric studies can be challenging due to several factors:
Ethical Considerations: Conducting trials in children requires careful ethical considerations, including obtaining informed consent from parents or guardians and assent from older children. Heterogeneity: The pediatric population is heterogeneous, with significant variations in age, development, and health status, which can complicate trial design and reporting. Sample Size: Recruiting a sufficient number of participants can be difficult, especially for rare conditions or specific age groups. Outcome Measures: Choosing appropriate and meaningful outcome measures that reflect the unique aspects of child health and development.
