Wiskott-Aldrich Syndrome is caused by mutations in the WAS gene located on the X chromosome. This gene is responsible for producing the Wiskott-Aldrich Syndrome protein (WASP), which plays a crucial role in the function of various cells in the immune system, including platelets and white blood cells. Mutations in the WAS gene lead to defective or absent WASP, resulting in the clinical manifestations of the syndrome.
