While providing adequate oxygen is crucial, excessive FiO2 can lead to complications, particularly in pediatric patients:
Oxygen Toxicity: High FiO2 levels over prolonged periods can cause lung damage, known as bronchopulmonary dysplasia in neonates. Retinopathy of Prematurity (ROP): Excessive oxygen levels can lead to abnormal retinal development in premature infants. Hyperoxia: Elevated oxygen levels can cause oxidative stress and cellular damage. Absorption Atelectasis: High oxygen concentrations can lead to alveolar collapse.
