What are the Risks Associated with Barbiturate Use in Neonates?
The use of barbiturates in neonates carries several risks, including respiratory depression, hypotension, and potential for long-term neurodevelopmental issues. Neonates have immature liver and kidney function, which can affect the metabolism and excretion of barbiturates, leading to a risk of accumulation and toxicity. Additionally, the sedative effects can make it difficult to assess the neonate’s neurological status accurately.
