What are the Clinical Manifestations of Neonatal HSV?
Neonatal HSV infection can present in three major forms:
1. Localized Skin, Eye, and Mouth (SEM) Disease: This form involves herpetic lesions on the skin, eyes, or mouth. It is the least severe but can progress to more serious forms if not treated. 2. Central Nervous System (CNS) Disease: Characterized by seizures, lethargy, irritability, and poor feeding. This form can lead to long-term neurological impairment. 3. Disseminated Disease: This is the most severe form, involving multiple organs such as the liver, lungs, and brain. It often presents with symptoms of sepsis and has a high mortality rate.
