Despite significant progress, GPEI faces several challenges:
Geopolitical Instability: Conflict and insecurity in certain regions hinder vaccination efforts. Vaccine Hesitancy: Misinformation and cultural resistance can reduce vaccination uptake. Logistical Issues: Delivering vaccines to remote and hard-to-reach areas can be difficult. Funding: Sustaining financial support for ongoing GPEI activities is essential for success. Vaccine-Derived Poliovirus: Rare cases of vaccine-derived poliovirus (VDPV) can occur, requiring vigilant monitoring and response.
