Microbiome-based interventions aim to modify or support the microbiome to improve health outcomes. In pediatrics, these interventions include:
- Probiotics: Live beneficial bacteria that can help restore the balance of the gut microbiome. Common strains used in pediatrics include _Lactobacillus_ and _Bifidobacterium_. - Prebiotics: Non-digestible food components that promote the growth of beneficial microbes. Examples include fiber-rich foods such as fruits, vegetables, and whole grains. - Synbiotics: A combination of probiotics and prebiotics designed to synergistically enhance the microbiome. - Fecal Microbiota Transplantation (FMT): The transfer of stool from a healthy donor to the gastrointestinal tract of a patient. Although more commonly used in adults, FMT is being explored for pediatric conditions like _Clostridium difficile_ infection. - Dietary Modifications: Introducing or eliminating certain foods to influence the microbiome. For instance, increasing the intake of fermented foods can introduce beneficial bacteria.
