The pediatric microbiome refers to the diverse community of microorganisms, including bacteria, viruses, fungi, and other microbes, that inhabit the bodies of children. These microbes play a crucial role in various aspects of health, including digestion, immune function, and even brain development. The composition of the microbiome changes significantly from infancy through childhood and can be influenced by factors such as mode of delivery (cesarean vs. vaginal birth), diet, antibiotic use, and environmental exposures.