- Infections: Exposure to bacteria, viruses, and other pathogens can lead to conditions such as neonatal sepsis. - Environmental Factors: Pollutants, toxins, and poor air quality can affect a newborn's health. - Maternal Health: Maternal conditions like diabetes, hypertension, and infections can impact the newborn. - Genetic Factors: Family history and genetic predispositions can increase the risk of certain disorders.