The treatment of MPGN in children involves addressing the underlying cause, if identified, and managing the symptoms. Options include:
Immunosuppressive therapy, such as corticosteroids and cyclophosphamide, especially for immune-mediated forms. Antiviral treatment for MPGN associated with viral infections. Plasma exchange or eculizumab for complement-mediated MPGN. Supportive care, including antihypertensive medications, diuretics, and dietary modifications.