Mechanical ventilation, while lifesaving, can contribute to lung injury through several mechanisms: 1. Volutrauma: Overdistension of alveoli caused by excessive tidal volumes. 2. Barotrauma: Damage due to high airway pressures. 3. Atelectrauma: Injury from repetitive opening and closing of alveoli. 4. Oxygen Toxicity: High concentrations of oxygen can exacerbate inflammatory responses.
These mechanisms collectively contribute to [ventilator-induced lung injury]() (VILI), which is a critical concern in neonatal care.
