Optimizing MAP involves balancing several ventilatory parameters: - Positive End-Expiratory Pressure (PEEP): Increasing PEEP can help improve oxygenation by keeping alveoli open during expiration. - Inspiratory Time (TI): Extending TI allows more time for gas exchange but must be balanced to avoid auto-PEEP. - Peak Inspiratory Pressure (PIP): Adjusting PIP can directly affect MAP but must be managed to avoid barotrauma. - Respiratory Rate (RR): Increasing RR can increase MAP but may also lead to hyperventilation and respiratory alkalosis.
