In neonates, particularly those with conditions like Respiratory Distress Syndrome (RDS), careful management of MAP is vital. Neonatal lungs are more susceptible to injury from high MAP due to their fragility and the presence of surfactant deficiency. Non-invasive ventilation strategies, such as Continuous Positive Airway Pressure (CPAP), may be used to maintain adequate MAP without the risks associated with invasive mechanical ventilation.