Diagnosis of uremia involves a combination of clinical evaluation and laboratory tests. Blood tests are crucial for assessing levels of blood urea nitrogen (BUN) and creatinine, which are elevated in uremia. A comprehensive metabolic panel can help evaluate electrolyte imbalances and acid-base status. Urinalysis may provide clues about the underlying cause. Imaging studies, such as ultrasound or MRI, can assess structural abnormalities in the kidneys.