Are There Any Specific Considerations for Dosing in Neonates?
Yes, dosing in neonates requires careful consideration due to their unique pharmacokinetics and pharmacodynamics. Factors like gestational age, weight, organ maturity, and metabolic rate must be taken into account. Neonates often require lower doses per kilogram of body weight compared to older children and adults. Close monitoring and adjustments are essential to avoid toxicity and ensure efficacy.