The significance of the APOE gene in Pediatrics extends beyond its role in lipid metabolism. Variants in this gene can influence a child's risk for developing certain conditions both in childhood and later in life. For instance, children carrying the APOE ε4 allele may have an increased risk of developing cardiovascular issues early. Additionally, the APOE gene has been studied in the context of neurodevelopmental disorders, cognitive function, and even response to infections.
