SIMV is particularly beneficial in neonates due to their underdeveloped respiratory systems. Conditions such as Neonatal Respiratory Distress Syndrome (RDS), Bronchopulmonary Dysplasia (BPD), and Apnea of Prematurity can compromise an infant's ability to breathe effectively. By combining mandatory and spontaneous breaths, SIMV helps to ensure adequate ventilation and oxygenation while promoting natural breathing efforts.