In the context of pediatrics, GDNF is particularly significant because it is involved in the early development of the nervous system. Proper levels of GDNF are essential for the growth and survival of motor neurons and dopaminergic neurons, which are critical for motor control and cognitive functions. Understanding the role of GDNF can help in diagnosing and treating pediatric neurological conditions such as spinal muscular atrophy (SMA) and autism spectrum disorders (ASD).
