Certain groups of children are at higher risk and require regular surveillance:
Children with genetic syndromes such as Beckwith-Wiedemann Syndrome, Li-Fraumeni Syndrome, or Neurofibromatosis Type 1. Children with a family history of cancer, particularly if it involves multiple family members or early-onset cancers. Survivors of childhood cancers who received treatments that increase the risk of secondary malignancies, such as radiation therapy.