Glucose administration is necessary in several situations: - Hypoglycemia: This is a condition characterized by abnormally low blood glucose levels. It can cause symptoms such as irritability, tremors, sweating, confusion, and in severe cases, seizures or unconsciousness. - Diabetes Mellitus: Children with diabetes may require glucose when their blood sugar levels drop too low due to factors such as excessive insulin administration or missed meals. - Metabolic Disorders: Certain genetic conditions, like glycogen storage diseases, may necessitate glucose administration to manage blood sugar levels. - Critical Illness: Children in intensive care units with conditions like sepsis or liver failure may require glucose to maintain adequate energy supply. - Prolonged Fasting: Situations where a child cannot eat for extended periods, such as preoperative fasting or gastrointestinal disorders.