When Are Platelet Transfusions Needed in Neonates?
Platelet transfusions are commonly required in neonates with conditions such as neonatal alloimmune thrombocytopenia (NAIT), sepsis, intraventricular hemorrhage (IVH), and other hematological disorders. They are crucial when platelet counts drop below certain thresholds, typically What Are the Risks Associated with Platelet Transfusions? While life-saving, platelet transfusions carry risks such as infection, allergic reactions, and transfusion-related acute lung injury (TRALI). Additionally, there is a risk of alloimmunization, where the neonatal immune system develops antibodies against transfused platelets, complicating future transfusions.
