desmosomes

What Pediatric Conditions are Associated with Desmosomes?

Several pediatric conditions are linked to defects or dysfunctions in desmosomes. Some of the notable conditions include:
Epidermolysis Bullosa: A group of genetic disorders causing fragile skin that blisters easily.
Pemphigus Vulgaris: An autoimmune disorder where the immune system attacks the proteins in desmosomes, leading to skin blistering.
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC): A condition affecting the heart muscle, leading to arrhythmias and increased risk of sudden cardiac arrest.

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