1. Early Recognition: Identify signs of sepsis such as temperature instability, respiratory distress, and lethargy. 2. Blood Cultures: Obtain blood cultures before starting antibiotics. 3. Empiric Antibiotics: Initiate empiric antibiotic therapy based on local guidelines. 4. Supportive Care: Provide supportive care including fluids, oxygen, and hemodynamic support. 5. Monitoring and Adjustment: Monitor clinical response and adjust antibiotics based on culture results and clinical progress.