In pediatric oncology, miRNAs can act as either tumor suppressors or oncogenes. Dysregulation of miRNAs can lead to uncontrolled cell proliferation and cancer. For example, let-7 family of miRNAs is known to suppress oncogenes, whereas miR-155 promotes cancer cell survival and proliferation. Targeting these miRNAs could provide new therapeutic avenues for treating pediatric cancers.
