Can miRNAs Serve as Biomarkers for Pediatric Diseases?
Yes, miRNAs have the potential to serve as biomarkers for various pediatric diseases. Due to their stability in body fluids and their disease-specific expression patterns, miRNAs can be used to diagnose and monitor diseases. For instance, miR-21 has been implicated in pediatric cancers such as neuroblastoma and Wilms' tumor, making it a potential diagnostic and prognostic marker.