What is the recommended dosing for Dexmedetomidine in pediatric patients?
The dosing of dexmedetomidine in pediatric patients varies based on the clinical scenario:
For ICU sedation, an initial loading dose of 0.5-1 mcg/kg over 10 minutes followed by a maintenance infusion of 0.2-0.7 mcg/kg/hr is commonly used. For procedural sedation, a bolus dose of 1-2 mcg/kg over 10 minutes may be administered, followed by an infusion if needed.
It is essential to titrate the dose based on the patient's response and clinical condition.