Severe renal impairment, also known as chronic kidney disease (CKD), is a condition where the kidneys are unable to function properly. In pediatrics, this condition can significantly impact a child's growth, development, and overall health. The kidneys' primary role is to filter waste products and excess fluids from the blood, which are then excreted in urine. When the kidneys fail to perform these functions efficiently, it can lead to a buildup of harmful substances in the body.