Several factors can contribute to increased levels of 8-OHdG in children, including:
1. Environmental Pollutants: Exposure to air pollution, tobacco smoke, and heavy metals. 2. Diet: Poor dietary habits lacking in antioxidants. 3. Infections: Chronic infections that lead to sustained inflammation. 4. Lifestyle: Sedentary lifestyle and lack of physical activity. 5. Genetic Factors: Some children may be genetically predisposed to higher oxidative stress.